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2 definitions found
 for Plague spot
From The Collaborative International Dictionary of English v.0.48 :

  Plague \Plague\, n. [L. plaga a blow, stroke, plague; akin to
     Gr. ?, fr. ? to strike; cf. L. plangere to strike, beat. Cf.
     Plaint.]
     1. That which smites, wounds, or troubles; a blow; a
        calamity; any afflictive evil or torment; a great trail or
        vexation. --Shak.
        [1913 Webster]
  
              And men blasphemed God for the plague of hail.
                                                    --Wyclif.
        [1913 Webster]
  
              The different plague of each calamity. --Shak.
        [1913 Webster]
  
     2. (Med.) An acute malignant contagious fever, that often
        prevails in Egypt, Syria, and Turkey, and has at times
        visited the large cities of Europe with frightful
        mortality; hence, any pestilence; as, the great London
        plague. "A plague upon the people fell." --Tennyson.
        [1913 Webster]
  
     Cattle plague. See Rinderpest.
  
     Plague mark, Plague spot, a spot or mark of the plague;
        hence, a token of something incurable.
        [1913 Webster]

From WordNet (r) 3.0 (2006) :

  plague spot
      n 1: a spot on the skin characteristic of the plague

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